BDBM50477330 CHEMBL218756

SMILES CCCCCCCCCCn1c2ccc(Cl)cc2c2ccc(cc12)C(C)C(O)=O

InChI Key InChIKey=AMSKXPFBGSQUHE-UHFFFAOYSA-N

Data  8 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50477330   

TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50: >4.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  2.90E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  5.80E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  2.90E+3nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50: >4.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  5.80E+3nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta38 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  2.90E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataEC50:  5.80E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University Of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50: >4.00E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta40 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed