BDBM50478065 CHEMBL3085386

SMILES FC1(F)CC[C@@H](N(Cc2ccc(cc2)C(=O)NC2CC2)S(=O)(=O)c2ccc(Cl)cc2)C(=O)NC1

InChI Key InChIKey=MLWAXXGNCXTWGI-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478065   

TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478065(CHEMBL3085386)
Affinity DataIC50:  300nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed