BDBM50481286 CHEMBL596174

SMILES CN(C)Cc1cccc(\C=N\Nc2ncnc3sc(cc23)C(C)(C)C)n1

InChI Key InChIKey=LNWXQOGMNRICEK-LSHDLFTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481286   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50481286(CHEMBL596174)
Affinity DataIC50:  151nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50481286(CHEMBL596174)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of CDK2/Cyclin E expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed