BDBM50484273 CHEMBL1824104

SMILES CC1(C)Oc2ccc(CN(Cc3ccccc3)S(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)cc2C=C1

InChI Key InChIKey=PBGRCXZQTHMAOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484273   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50484273(CHEMBL1824104)
Affinity DataIC50:  508nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene preincubated for 1 hr under normoxia condition fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed