BDBM50490734 CHEMBL1863136::DNDI1402165

SMILES COc1ccccc1N1CCN(CC1)C(c1ccc(cc1)C(F)(F)F)c1cnccn1

InChI Key InChIKey=ZOOMOAJHSVDRKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490734   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490734(CHEMBL1863136 | DNDI1402165)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed