BDBM50492085 CHEMBL2396953
SMILES [H][C@]12Cc3n[nH]cc3[C@]([H])(N1S(=O)(=O)c1ccc(nc1)C(F)(F)F)c1c2cccc1F
InChI Key InChIKey=LPGNFEMHCAETQT-PBHICJAKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50492085
Affinity DataIC50: 0.400nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using Notch as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair