BDBM50496327 CHEMBL3126198

SMILES N[C@](C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1

InChI Key InChIKey=AUWUGRCKTQSGJY-HHHXNRCGSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496327   

TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50496327(CHEMBL3126198)
Affinity DataIC50:  56nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50496327(CHEMBL3126198)
Affinity DataKd:  85nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair