BDBM50496340 CHEMBL3124953

SMILES O[C@@](C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1

InChI Key InChIKey=QBITUTDDFZQXDO-MHZLTWQESA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496340   

TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50496340(CHEMBL3124953)
Affinity DataIC50:  529nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50496340(CHEMBL3124953)
Affinity DataKd:  952nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB