BDBM50496346 CHEMBL3126196

SMILES NC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1

InChI Key InChIKey=AUWUGRCKTQSGJY-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496346   

TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataKi:  58nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to biotinylated Menin (unknown origin) by biolayer interferometry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataIC50:  67nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50496346(CHEMBL3126196)
Affinity DataIC50:  185nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB