BDBM50499970 CHEMBL3741505

SMILES OC(=O)[C@@H]1CC[C@@H](CC1)Oc1ccc(cc1)C(=O)Nc1nnc(Nc2ccccc2)s1

InChI Key InChIKey=JINSGXWXKYXICS-RHNCMZPLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499970   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  3nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed