BDBM50503431 CHEMBL4471568::US11274074, Example 3 [Chemical Formula 7]

SMILES COc1ccccc1-c1nnc(COc2ccc(Cl)cc2C)o1

InChI Key InChIKey=KCYMMMKPVASVQZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503431   

TargetAnoctamin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.24E+4nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.94E+4nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed