BDBM50503780 CHEMBL4475315
SMILES Cc1cc(N2CC(CC2=O)C(=O)N\N=C\c2ccc(Br)cc2)c(Cl)c(C)c1S(N)(=O)=O
InChI Key InChIKey=SPSNHNYTLIKLAR-PGGKNCGUSA-N
Data 18 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50503780
Affinity DataKd: 0.0280nMAssay Description:Binding affinity to recombinant human CA2 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.120nMAssay Description:Binding affinity to recombinant human CA4 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0310nMAssay Description:Binding affinity to recombinant human CA7 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0710nMAssay Description:Binding affinity to recombinant human CA9 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.690nMAssay Description:Binding affinity to recombinant human CA12 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.0760nMAssay Description:Binding affinity to recombinant human CA13 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.640nMAssay Description:Binding affinity to recombinant human CA1 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to recombinant human CA9 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+3nMAssay Description:Binding affinity to recombinant human CA12 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding affinity to recombinant human CA13 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 560nMAssay Description:Binding affinity to recombinant human CA1 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to recombinant human CA4 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding affinity to recombinant human CA7 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University Of Technology
Curated by ChEMBL
Kaunas University Of Technology
Curated by ChEMBL
Affinity DataKd: 0.00480nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) assessed as intrinsic di...More data for this Ligand-Target Pair
Affinity DataKd: 920nMAssay Description:Binding affinity to recombinant human CA6 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to recombinant human CA2 by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Binding affinity to recombinant human CA6 assessed as intrinsic dissociation constant by DSF-based fluorescence thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Kaunas University Of Technology
Curated by ChEMBL
Kaunas University Of Technology
Curated by ChEMBL
Affinity DataKd: 7.70nMAssay Description:Binding affinity to recombinant full length N-terminal His6x-tagged human CA5B expressed in Escherichia coli Rosetta 2 (DE3) by DSF-based fluorescenc...More data for this Ligand-Target Pair