BDBM50506676 CHEMBL4443969

SMILES Oc1ccccc1C1CC(=NN1c1nc(cs1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=SBNQWXPTENPAGN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506676   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506676(CHEMBL4443969)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of recombinant human MMP-2 preincubated for 10 mins followed by Mca-PLGL-Dpa-AR-NH2 substrate addition and measured for 5 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506676(CHEMBL4443969)
Affinity DataIC50:  6.25E+4nMAssay Description:Inhibition of recombinant human MMP-8 using Mca-PLGL-Dpa-AR-NH2 as substrate preincubated for 10 mins followed by substrate addition and measured for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing Agricultural University

Curated by ChEMBL
LigandPNGBDBM50506676(CHEMBL4443969)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of recombinant human MMP-2 preincubated for 10 mins followed by Mca-PLGL-Dpa-AR-NH2 substrate addition and measured for 5 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed