BDBM50507996 CHEMBL4441182

SMILES COc1cnc2c(ncnc2c1)C1CCN(CC1)C(=O)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=GUVFZEDBARKYKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507996   

TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50507996(CHEMBL4441182)
Affinity DataIC50:  540nMAssay Description:Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measurin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50507996(CHEMBL4441182)
Affinity DataIC50:  98nMAssay Description:Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed