BDBM50509708 CHEMBL4458648

SMILES S=C(NCc1ccccc1)NNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=GHGXCYPXBDQVRC-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50509708   

TargetAcetylcholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataKi:  121nMAssay Description:Mixed type inhibition of recombinant human AChE assessed as dissociation constant using acetylthiocholine iodide as substrate incubated for 10 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataKi:  253nMAssay Description:Mixed type inhibition of recombinant human AChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataIC50:  622nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataIC50:  33nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for 180 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataIC50:  110nMAssay Description:Inhibition of ovine COX -2 by colorimetric inhibitor screening assay kit methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataIC50:  8.33E+3nMAssay Description:Inhibition of ovine COX -1 by colorimetric inhibitor screening assay kit methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509708(CHEMBL4458648)
Affinity DataIC50:  218nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed