BDBM50510569 CHEMBL4533153

SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key InChIKey=OPMJBWVXRQIVBZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50510569   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  400nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  375nMAssay Description:Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  242nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  418nMAssay Description:Inhibition of FLT1 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  2nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  356nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  380nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
School Of Marine Science And Technology

Curated by ChEMBL
LigandPNGBDBM50510569(CHEMBL4533153)
Affinity DataIC50:  95nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed