BDBM50510996 CHEMBL3105168

SMILES CN1CCN(CC1)c1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)Nc1cccnc1

InChI Key InChIKey=SQVTVTGQSWPKQE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510996   

TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50510996(CHEMBL3105168)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi Tulahuen C4 CYP51 expressed in Escherichia coli HMS174 using [3H]-sterol as substrate in presence of NADPH by reverse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50510996(CHEMBL3105168)
Affinity DataKd:  1.32E+3nMAssay Description:Binding affinity to full length Trypanosoma cruzi Tulahuen C4 C-terminal His-tagged CYP51 expressed in Escherichia coli HMS174 (DE3) assessed as indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed