BDBM50513674 CHEMBL4458485

SMILES CN1C(=O)\C(=N/c2ccc(NC(=O)Nc3ccc(cc3)S(N)(=O)=O)cc2)c2cc(Cl)ccc12

InChI Key InChIKey=HWQDCIWDPIJWPP-QQTULTPQSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50513674   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  5.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  6.30nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  407nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataKi:  824nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50513674(CHEMBL4458485)
Affinity DataIC50:  261nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) as substrate measured after 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed