BDBM50518926 CHEMBL4536608

SMILES O[C@@H](CNc1cc(=O)oc2ccccc12)CN1CCN(CC1)c1nccc2ccc(F)cc12

InChI Key InChIKey=SJCCHHKLFODASY-IBGZPJMESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50518926   

TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518926(CHEMBL4536608)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518926(CHEMBL4536608)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518926(CHEMBL4536608)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518926(CHEMBL4536608)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed