BDBM50519162 CHEMBL4573716

SMILES Cc1cc(C)n(n1)-c1cccc(c1)[C@H](CC([O-])=O)C[N@+]1(C)CC[C@@H](CCc2ccc3CCCNc3n2)C1

InChI Key InChIKey=BXOSGYRJKCYDLH-UYMYSODTSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50519162   

TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataKi:  0.174nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of integrin alphavbeta5 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to human vitronectin incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of integrin alphavbeta1 (unknown origin) expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50519162(CHEMBL4573716)
Affinity DataIC50:  63nMAssay Description:Inhibition of integrin alphavbeta8 (unknown origin) expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP1 (242 to 252 amin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed