BDBM50521051 CHEMBL4439974

SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)COC(C)=O

InChI Key InChIKey=MFIBXOBOSOKFSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50521051   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50521051(CHEMBL4439974)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of recombinant human wild type GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system after 1 hr by kinase trac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Parma

Curated by ChEMBL
LigandPNGBDBM50521051(CHEMBL4439974)
Affinity DataIC50:  34nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed