BDBM50525283 CHEMBL4458557
SMILES CN1CCN(CC1)c1ccc(Nc2ccc(N3CCCCC3)c(Oc3ccc(C)c(NC(=O)C=C)c3)n2)cc1
InChI Key InChIKey=LTZMKTRBHXYEOB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50525283
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of cathepsin C in human THP1 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of cathepsin C in human U937 cells using H-Gly-Phe-AFC as substrate preincubated for 4 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
National Institute Of Biological Sciences (Nibs)
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CatL-activated recombinant human C-terminal His10-tagged cathepsin C (25 to 463 residues) expressed in mouse myeloma cells using Gly-Ph...More data for this Ligand-Target Pair