BDBM50526258 CHEMBL4455995

SMILES Cl.OC(=O)C1CCCN(CCO\N=C\c2ccccc2-c2ccc(Cl)cc2Cl)C1

InChI Key InChIKey=AILJISZBVRATFZ-KEJAMGHHSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50526258   

TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataKi:  10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  7.08E+4nMAssay Description:Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed