BDBM50527041 CHEMBL4447977

SMILES CC(=O)NCCN(Cc1ccccc1)C(=O)c1nn(C)c-2c1COc1ccccc-21

InChI Key InChIKey=JGSWAGMWZXMFQW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527041   

TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527041(CHEMBL4447977)
Affinity DataEC50:  480nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50527041(CHEMBL4447977)
Affinity DataEC50:  690nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed