BDBM50531942 CHEMBL4454064

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2c(Oc3ccc4cc(ccc4c3C2(C)C)-c2cnc([nH]2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)c1

InChI Key InChIKey=MICFIDOAUGVKSC-HOSOATPESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531942   

TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531942(CHEMBL4454064)
Affinity DataEC50:  18nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531942(CHEMBL4454064)
Affinity DataEC50:  0.00290nMAssay Description:Inhibition of NS5A in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531942(CHEMBL4454064)
Affinity DataEC50:  11nMAssay Description:Inhibition of NS5A in HCV genotype 2b assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed