BDBM50531962 CHEMBL4577346

SMILES CCC1(CC)c2ccc(cc2Oc2cc3ccc(cc3cc12)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=CITBIKHEQYOEMB-MXAOVZPPSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531962   

TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531962(CHEMBL4577346)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of NS5A in HCV genotype 3a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531962(CHEMBL4577346)
Affinity DataEC50:  0.00200nMAssay Description:Inhibition of NS5A in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531962(CHEMBL4577346)
Affinity DataEC50:  4.5nMAssay Description:Inhibition of NS5A in HCV genotype 2b assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Merck

Curated by ChEMBL
LigandPNGBDBM50531962(CHEMBL4577346)
Affinity DataEC50:  3.30nMAssay Description:Inhibition of NS5A Y93H mutant in HCV genotype 1a assessed as decrease in viral replicationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed