BDBM50538485 CHEMBL4647075::US11396496, Compound C11

SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc(CCC(O)=O)c2ccccc12

InChI Key InChIKey=XTZHHZTZEHWJCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538485   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50538485(CHEMBL4647075 | US11396496, Compound C11)
Affinity DataIC50:  6.00E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50538485(CHEMBL4647075 | US11396496, Compound C11)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed