BDBM50544692 CHEMBL4638071

SMILES Clc1ccc(CNC(=O)[C@@H]2CCC(=O)N2c2nccs2)c(Cl)c1

InChI Key InChIKey=SMNVKLAVWUZGJF-LBPRGKRZSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544692   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataKi:  489nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataIC50:  2.39E+3nMAssay Description:Displacement of [3H]-A804598 from human P2X7 expressed in human HEK293 cell membrane incubated for 1 hr by microplate scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50544692(CHEMBL4638071)
Affinity DataIC50:  415nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed