BDBM50545264 CHEMBL4643407

SMILES CSc1nc2ccccc2n1-c1csc(NC\C(C)=N\N=c2/scc(-c3ccc(C)cc3)n2-c2ccccc2)n1

InChI Key InChIKey=XBMMEANMEQOLTB-VSCZWMNHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545264   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545264(CHEMBL4643407)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Assiut University

Curated by ChEMBL
LigandPNGBDBM50545264(CHEMBL4643407)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed