BDBM50546133 CHEMBL4750688
SMILES CN(C)c1ccc(CC(=O)N[C@@H]2CNC[C@H]2c2ccc(cc2)C(F)(F)F)cc1
InChI Key InChIKey=XORRDVHOURHODX-RBUKOAKNSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50546133
Affinity DataIC50: 4.54E+4nMAssay Description:Inhibition of recombinant human CYP2C19 expressed in baculovirus infected insect cells using s-mephenytoin as substrate incubated for 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 9.81E+4nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cells using tolbutamide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Saint Louis University
Curated by ChEMBL
Saint Louis University
Curated by ChEMBL
Affinity DataIC50: 5.91E+3nMAssay Description:Displacement of Tracer Red from human ERG incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using phenacetin as substrate incubated for 30 mins in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cells using midazolam as substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in baculovirus infected insect cells using dextromethorphan as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair