BDBM50546135 CHEMBL4759278
SMILES CN(C)c1ccc(CC(=O)N[C@@H]2CNC[C@H]2c2ccc(cc2)C(C)(F)F)cc1
InChI Key InChIKey=WQTOGFREMHSJJS-VQTJNVASSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50546135
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of recombinant human CYP2C19 expressed in baculovirus infected insect cells using s-mephenytoin as substrate incubated for 30 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cells using tolbutamide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Saint Louis University
Curated by ChEMBL
Saint Louis University
Curated by ChEMBL
Affinity DataIC50: 2.81E+3nMAssay Description:Displacement of Tracer Red from human ERG incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cells using phenacetin as substrate incubated for 30 mins in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cells using midazolam as substrate incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in baculovirus infected insect cells using dextromethorphan as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair