BDBM50546584 CHEMBL4760001

SMILES CN(CCN)Cc1c(cnc2ncn(-c3cccc(O)c3)c(=O)c12)-c1cc(C)cc(C)c1

InChI Key InChIKey=UHWCCSHGUZLTTA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546584   

TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546584(CHEMBL4760001)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))TBA
LigandPNGBDBM50546584(CHEMBL4760001)
Affinity DataEC50:  20nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546584(CHEMBL4760001)
Affinity DataEC50:  36nMAssay Description:Inhibitory activity against Dihydrofolate reductase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546584(CHEMBL4760001)
Affinity DataEC50:  39.8nMAssay Description:Agonist activity at human SST2 expressed in CHOK1 cells assessed as inhibition of NKH477-stimulated intracellular cAMP levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed