BDBM50548189 CHEMBL4761101

SMILES COc1ccc(F)c(c1)-c1ccc(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)nc1C1=CCCC1(C)C

InChI Key InChIKey=WSECGFLGUSNJDA-SANMLTNESA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548189   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Developmen

Curated by ChEMBL
LigandPNGBDBM50548189(CHEMBL4761101)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Janssen Research & Developmen

Curated by ChEMBL
LigandPNGBDBM50548189(CHEMBL4761101)
Affinity DataEC50:  45nMAssay Description:Agonist activity at rat GPR40 transfected in HEK293 cells assessed as increase in intracellular calcium level incubated for 1 hr by Fluo-8 dye based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed