BDBM50549254 CHEMBL4745104

SMILES CN(C)CCn1cc2cc(NC(=O)c3coc(n3)-c3ccnc(C)c3)c(cc2n1)C(C)(C)O

InChI Key InChIKey=OVBBOHRFQUWACF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549254   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549254(CHEMBL4745104)
Affinity DataIC50:  59nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549254(CHEMBL4745104)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed