BDBM50549255 CHEMBL4754306

SMILES CN(C)CCn1cc2cc(NC(=O)c3nc(cs3)C(F)(F)F)c(cc2n1)C(C)(C)O

InChI Key InChIKey=XFKVPKAIRYWQSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549255   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549255(CHEMBL4754306)
Affinity DataIC50:  198nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549255(CHEMBL4754306)
Affinity DataIC50:  35nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed