BDBM50549729 CHEMBL4776293
SMILES CN1CCN(CC1)c1ccc(Nc2ncc3CC4(CCNC4=O)N(C4CCCC4)c3n2)cc1F
InChI Key InChIKey=HFPVKHFOWKBZPW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50549729
Affinity DataIC50: 47nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/cyclinD3 (1 to 292 residues) expressed in baculovirus expression syste...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant human full-length GST-tagged CDK4/cyclinD1 expressed in baculovirus expression system using PEP as substrate incubated for ...More data for this Ligand-Target Pair