BDBM50549729 CHEMBL4776293

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3CC4(CCNC4=O)N(C4CCCC4)c3n2)cc1F

InChI Key InChIKey=HFPVKHFOWKBZPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549729   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549729(CHEMBL4776293)
Affinity DataIC50:  47nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged Cyclin-T1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549729(CHEMBL4776293)
Affinity DataIC50:  258nMAssay Description:Inhibition of human full-length N-terminal GST tagged CDK6 (1 to 326 residues)/cyclinD3 (1 to 292 residues) expressed in baculovirus expression syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50549729(CHEMBL4776293)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant human full-length GST-tagged CDK4/cyclinD1 expressed in baculovirus expression system using PEP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed