BDBM50554076 CHEMBL4795963

SMILES COc1nc(ccc1-n1cnc(C)c1)-c1csc(Nc2c3CCCCc3nn2C2CCC2)n1

InChI Key InChIKey=OPBCSQTYQHKIFO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50554076   

TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50:  660nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50:  64nMAssay Description:Modulation of gamma secretase in human SH-SY5Y cells overexpressing wild type APP751 assessed as inhibition of amyloid beta (35 to 42 residues) forma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554076(CHEMBL4795963)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed