BDBM50554105 CHEMBL4762589

SMILES COc1nc(ccc1-n1cnc(C)c1)-c1csc(Nc2c3CCCc3nn2C(C)(C)C)n1

InChI Key InChIKey=NVRPIFOUCJMRHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554105   

TargetPresenilin-1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50554105(CHEMBL4762589)
Affinity DataIC50:  62nMAssay Description:Modulation of gamma secretase in human SH-SY5Y cells overexpressing wild type APP751 assessed as inhibition of amyloid beta (35 to 42 residues) forma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed