BDBM50554231 CHEMBL4796870

SMILES Cc1ccc(cc1)-c1cnc(C[C@H]2CCNC2)nc1-c1ccc(cc1)C#N

InChI Key InChIKey=NYZDKAOVNFYTJM-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554231   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554231(CHEMBL4796870)
Affinity DataIC50:  2nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Fount Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554231(CHEMBL4796870)
Affinity DataIC50:  28nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as induction of cell differentiation by measuring CD11b expression incubated for 96 hrs by FACS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed