BDBM50556536 CHEMBL4781965
SMILES COc1ccc(cc1)-c1cc(C(=O)NC2CCCCCC2)c(=O)n(Cc2ccc(F)cc2)c1C
InChI Key InChIKey=YPSDNJQXGBDEBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50556536
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Affinity DataEC50: 103nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Antagonist activity at human CB2R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 81nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
Affinity DataEC50: 192nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
Affinity DataEC50: 711nMAssay Description:Competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as rightward shift of N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-f...More data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Non-competitive antagonist activity at human CB2R expressed in CHO cell membranes assessed as N-cycloheptyl-1,2-dihydro-1-(4-fluorobenzyl)-6-methyl-2...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using [glycerol-1,2,3-3H]2-OG as substrate preincubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FAAH in human U937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Antagonist activity at human CB1R expressed in CHO cell membranes preincubated for 30 mins followed by GTPgammaS addition and measured after 90 mins ...More data for this Ligand-Target Pair