BDBM50558488 CHEMBL4794972
SMILES Cc1c(Br)cc(NC(=O)C(c2ccccc2)S(O)(=O)=O)cc1Br
InChI Key InChIKey=DWUBYIFZVUOBSF-UHFFFAOYSA-N
Data 50 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 50 hits for monomerid = 50558488
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate in...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Rattus norvegicus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTP1B (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged TC-PTP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged SHP1 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged LYP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged HePTP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged FAP1 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 7.23E+4nMAssay Description:Inhibition of His-tagged PTP-PEST (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CD45 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged LAR (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPalpha (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPbeta (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated fo...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPgamma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPepsilon (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged VHR (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 23(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged VHZ (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
TargetRNA polymerase II subunit A C-terminal domain phosphatase SSU72(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged SSu72 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Homo sapiens)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PP5 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of FAP-1(unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 3(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPH1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of HePTP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of LYP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of TC-PTP (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 at 10 uM using pNPP as substrate incubated for 10 mins by microplate reader...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of PEST(unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CD45 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of LAR(unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPbeta (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPgamma (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPepsilon (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VHR (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 23(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VHZ (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
TargetRNA polymerase II subunit A C-terminal domain phosphatase SSU72(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SSU72 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged SHP2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair