BDBM50559478 CHEMBL4800629

SMILES CCO[C@H]1CC[C@@H](CC1)Nc1cc2N(C)c3ccccc3C(=O)N(C)c2cn1

InChI Key InChIKey=PAKQVNTYVFSSIE-WKILWMFISA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50559478   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559478(CHEMBL4800629)
Affinity DataEC50:  2.74E+3nMAssay Description:Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced TNFalpha secretion preincubated for 1 hr followed by LPS-stimulation and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559478(CHEMBL4800629)
Affinity DataIC50:  9.99E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50559478(CHEMBL4800629)
Affinity DataIC50:  81nMAssay Description:Inhibition of recombinant human ERK5 using myelin basic protein as substrate by [gamm33P]ATP based HotSpot radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed