BDBM50563732 CHEMBL4776545::US11453681, Compound C60
SMILES Cc1c2NCCOc2ncc1-c1ccc2NC(=O)\C(=C/c3cc4cnccc4[nH]3)c2c1
InChI Key InChIKey=DLWLALBXXKNZFF-ZDLGFXPLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50563732
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0600nMAssay Description:The enzymatic activity of human HPK1 (MAP4K1) was monitored in a biochemical assay in the presence or absence of compounds and using a synthetic pept...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed b...More data for this Ligand-Target Pair