BDBM50563732 CHEMBL4776545::US11453681, Compound C60

SMILES Cc1c2NCCOc2ncc1-c1ccc2NC(=O)\C(=C/c3cc4cnccc4[nH]3)c2c1

InChI Key InChIKey=DLWLALBXXKNZFF-ZDLGFXPLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563732   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50563732(CHEMBL4776545 | US11453681, Compound C60)
Affinity DataIC50:  0.0600nMAssay Description:The enzymatic activity of human HPK1 (MAP4K1) was monitored in a biochemical assay in the presence or absence of compounds and using a synthetic pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50563732(CHEMBL4776545 | US11453681, Compound C60)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed