BDBM50568726 CHEMBL4854181

SMILES Cc1[nH]c(C(=O)Nc2nc3c(OCc4ccccc4)cc(cc3s2)C(O)=O)c(Cl)c1Cl

InChI Key InChIKey=QJJVAUMJKWWKTD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568726   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50: <10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568726(CHEMBL4854181)
Affinity DataIC50:  16nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB