BDBM50569655 CHEMBL4869836::US11802133, Example 279

SMILES [H][C@@]12CN(CC[C@]1([H])OCC(=O)N2)C(=O)N1CC(CCc2ccc(cc2F)C(F)(F)F)C1

InChI Key InChIKey=LULFUMCUGHSWTN-SJORKVTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569655   

TargetMonoglyceride lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50569655(CHEMBL4869836 | US11802133, Example 279)
Affinity DataIC50:  1nMAssay Description:The 4-NPA assay was carried out in 384 well assay plates (black with clear bottom, non-binding surface treated, Corning Ref. 3655) in a total volume ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50569655(CHEMBL4869836 | US11802133, Example 279)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant MAGL (unknown origin) using 4-Nitrophenlyacetate as substrate incubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed