BDBM50571897 CHEMBL4866705

SMILES Nc1nc(Cl)c2nc(O)n(Cc3ccc(Br)cc3F)c2n1

InChI Key InChIKey=CCUHAWKQXDIYIR-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50571897   

TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571897(CHEMBL4866705)
Affinity DataIC50:  58nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEndoplasmin(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571897(CHEMBL4866705)
Affinity DataIC50:  494nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal Grp94 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50571897(CHEMBL4866705)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant N-terminal HSP90alpha (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed