BDBM50575780 CHEMBL4878039
SMILES Cn1cncc1-c1cc(F)ccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O
InChI Key InChIKey=ZBWZIBATIOSFOY-FQEVSTJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50575780
Affinity DataKi: 0.75nMAssay Description:Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+3nMAssay Description:Inhibition of recombinant human pancreatic CPB incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetCarboxypeptidase N catalytic chain(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataKi: 2.82E+5nMAssay Description:Inhibition of recombinant human plasma CPN incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 389nMAssay Description:Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair