BDBM50576853 CHEMBL4859206
SMILES Oc1ccccc1-c1nc(no1)-c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=BPZMTSRVPSGZIV-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50576853
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University
Curated by ChEMBL
Alexandria University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair