BDBM50576853 CHEMBL4859206

SMILES Oc1ccccc1-c1nc(no1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BPZMTSRVPSGZIV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50576853   

TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNADPH oxidase 4(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576853(CHEMBL4859206)
Affinity DataIC50:  11nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed