BDBM50580006 CHEMBL5090730::US20230357269, Example 14

SMILES O=C1NCCCOc2ccc3[nH]nc(-c4cc(CO1)cc(c4)N1CCC4(COC4)C1)c3c2

InChI Key InChIKey=UJFAWAPCPLQEPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580006   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM50580006(CHEMBL5090730 | US20230357269, Example 14)
Affinity DataIC50: <10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Les Laboratoires Servier

US Patent
LigandPNGBDBM50580006(CHEMBL5090730 | US20230357269, Example 14)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human LRRK2 using LRRKtide peptide and ATP as substrates incubated for 1 hrs by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed