BDBM50582532 CHEMBL5085545

SMILES Fc1cc(F)c(NC(=O)COc2ccc3cc(\C=C4\SC(=O)NC4=O)ccc3c2)c(Br)c1

InChI Key InChIKey=VBAPRGNDRKQXHC-NGYBGAFCSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582532   

TargetHistone deacetylase 4(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582532(CHEMBL5085545)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582532(CHEMBL5085545)
Affinity DataEC50:  245nMAssay Description:Partial agonist activity at Gal4-fused human PPARgamma LBD in HepG2 cells assessed as transactivation incubated for 20 hrs measured by luminometerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582532(CHEMBL5085545)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed