BDBM50582532 CHEMBL5085545
SMILES Fc1cc(F)c(NC(=O)COc2ccc3cc(\C=C4\SC(=O)NC4=O)ccc3c2)c(Br)c1
InChI Key InChIKey=VBAPRGNDRKQXHC-NGYBGAFCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50582532
TargetHistone deacetylase 4(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 245nMAssay Description:Partial agonist activity at Gal4-fused human PPARgamma LBD in HepG2 cells assessed as transactivation incubated for 20 hrs measured by luminometerMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Bharati Vidyapeeth'S College Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair